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This study evaluates how well the Personal and Social Performance Scale (PSP) predicts outcomes on the Positive and Negative Syndrome Scale (PANSS) in schizophrenia patients.

March 23, 2026BMC Research NotesOpen Access

Predictive validity of the personal and social performance scale for PANSS outcomes in schizophrenia: a severity-stratified study

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Authors

KCKai-Da ChengNational Chung Cheng University FLFor-Wey LungJinwen University of Science and Technology

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Implication

Multicenter prospective study evaluates PSP's predictive validity for PANSS outcomes in schizophrenia, suggesting clinical monitoring benefits.

Key Points

This study evaluates how well the Personal and Social Performance Scale (PSP) predicts outcomes on the Positive and Negative Syndrome Scale (PANSS) in schizophrenia patients.
Conducted a 12-week multicenter prospective study
Included 763 patients receiving paliperidone treatment
Assessed baseline PANSS and PSP scores
Analyzed data using structural equation modeling
Patients with PSP scores ≥60 at week 12 had over a 20% reduction in PANSS scores
Lower PSP scores (<60) showed less symptom improvement
Symptom reduction correlated with better functional outcomes but not necessarily with improved quality of life

Cite This Study

Cheng et al. (2026) studied this question.

synapsesocial.com/papers/69c0e016fddb9876e79c1946 https://doi.org/10.1186/s13104-026-07773-y

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Implication

Multicenter prospective study evaluates PSP's predictive validity for PANSS outcomes in schizophrenia, suggesting clinical monitoring benefits.

Predictive validity of the personal and social performance scale for PANSS outcomes in schizophrenia: a severity-stratified study

Discussion

Member takes

Implication

Key Points

Cite This Study

Predictive validity of the personal and social performance scale for PANSS outcomes in schizophrenia: a severity-stratified study

Discussion

Member takes

Implication

Key Points

Cite This Study

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