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March 24, 2026European Respiratory Journal

Prediction of extubation outcome in neonates born prematurely or at term

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Authors

PBPrashanth BhatGRGerrard F. RaffertySHSimon Hannam

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Overview

Evaluates extubation success predictions in neonates using diaphragm measurements, suggesting varying effectiveness by birth term.

Key Points

  • The aim is to assess the effectiveness of diaphragm tension time indices in predicting extubation success in neonates born prematurely and at term.
  • Infants studied within six hours of extubation
  • TTdi measured via trans diaphragmatic pressure indicator
  • TTmus assessed through airway pressure readings from a pneumotachograph
  • Extubation failure defined as a need for reintubation within 48 hours
  • Forty-four infants were analyzed, of which eleven failed extubation
  • Median TTdi was significantly higher in infants who failed extubation (p=0.002)
  • Median TTmus was also higher in those who failed (p=0.031)
  • Both TTdi and TTmus had 94% sensitivity in term infants but only 72% in premature infants

Cite This Study

Bhat et al. (2014) studied this question.

synapsesocial.com/papers/69c2298daeb5a845df0d425bhttps://doi.org/10.1183/13993003/erj.44.suppl_58.277
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Diaphragm ultrasound: A predictor of extubation in head injury patients2024
  2. 2Ultrasound assessment of diaphragmatic function during weaning and after extubation in preterm newborns: brief report2026
  3. 3Role of Transthoracic Ultrasound in Predicting Weaning and Successful Extubating from Mechanical Ventilation in Neonatal Intensive Care Unit2026
  4. 4Association Between Diaphragm Ultrasound Measures and Extubation Outcomes in Neonates: A Systematic Review and Meta‐Analysis2026
  5. 5Point-of-Care Ultrasound Evaluation of Diaphragm as a Predictor of Extubation Success in Mechanically Ventilated, Malnourished, End-Stage Liver Disease Pretransplant Candidates—Observational Cohort Study2025