Distinct miRNA expression profiles in subcutaneous and visceral adipose tissue of gastrointestinal cancer patients and their modulation based on adiposity level assessed by CT-scan

This is the first study comparing both SAT and VAT microRNA from the same cancer patients, stratified by adiposity assessed via CT-scan, showing depot-specific miRNA regulation. Our findings indicate that VAT is prone to metabolic dysregulation, with miR-155 emerging as a potential indicator of visceral fat remodeling.