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This study aims to compare the effectiveness of succinylcholine and rocuronium for first-pass success during rapid sequence intubation.

Comparing Succinylcholine with Rocuronium for First-Pass Success During Rapid Sequence Intubation at an Academic Emergency Department

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This study aims to compare the effectiveness of succinylcholine and rocuronium for first-pass success during rapid sequence intubation.
Retrospective analysis of records from 2017 to 2021 at an academic emergency department.
Included patients underwent rapid sequence intubation with either succinylcholine or rocuronium.
Primary outcome was first-pass success and secondary outcome was clinically acceptable intubation conditions.
Logistic regression analysis was applied to compare outcomes between the two agents.
342 patients included: 201 received succinylcholine, 141 received rocuronium.
First-pass success rates were similar: 84.3% for succinylcholine, 82.9% for rocuronium (p=0.23).
Clinically acceptable intubation conditions also showed no significant difference (89.9% vs. 88.3%; p=0.19).
Adjustments for confounding factors maintained similar results for both outcomes.

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Retrospective study compares first-pass success of succinylcholine and rocuronium during intubation, suggesting similar outcomes.

Bakhsh et al. (2026) studied this question.

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