Why the study?
Does rocuronium provide comparable intubating conditions, onset time, and cardiovascular effects to succinylcholine in adult elective surgical patients?
Does rocuronium provide comparable intubating conditions, onset time, and cardiovascular effects to succinylcholine in adult elective surgical patients?
Succinylcholine provides a faster onset for intubation compared to rocuronium, though higher-dose rocuronium yields excellent intubating conditions with more persistent cardiovascular effects.
Succinylcholine remains preferable for fastest onset in elective intubation; challenges full equivalence while supporting higher-dose rocuronium for optimal conditions.
Background: The study was aimed to compare the effect on intubating conditions, onset, clinical duration and cardiovascular effects following administration of Succinylcholine and Rocuronium in Adult Elective Surgical patients. Materials and Methods: In a prospective randomised controlled trial, seventy five adult ASA grade I or II patients of either sex in the age group of 18-65 years undergoing elective surgery under general anaesthesia were given either succinylcholine 1mg/kg (group S), Rocuronium 0.6mg/kg (group R) or Rocuronium 0.9mg/kg (group R) after induction with thiopentone 4-6mg / kg body weight. Results and conclusion: The study revealed a statistically significant difference in onset time between the three groups: fastest in group S (52.8 15 sec) followed by R (102.6 40.8 sec) and R (163.2 58.2 sec) respectively. Intubating conditions were excellent to good in 92% patients in group S, 88% in group R and 100% in group R. Heart rate and mean arterial pressure were increased in all the three groups with persistence in group R+ > R > S.
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A 2007 study studied this question.
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