Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
March 25, 2026International Journal of SurgeryOpen Access

Global burden of liver cancer from 1990 to 2021 and 20-year projections: findings from the global burden of disease study 2021

View Full Paper
Ask AI
Bookmark
Share

Authors

YWY S WangYLYong LiLYLin Yang

Discussion

Loading...

Member takes

Overview

Analysis shows rising liver cancer incidence globally, with need for region-specific prevention strategies.

Key Points

  • This analysis aims to assess the global incidence and mortality of liver cancer from 1990 to 2021 and project future trends.
  • Evaluated liver cancer data across 204 countries using the Global Burden of Disease Study 2021.
  • Calculated age-standardized rates and percentage changes for incidence and mortality.
  • Utilized Nordpred and Bayesian Age-Period-Cohort models for future projections.
  • Global liver cancer incidence rose by 0.115% annually from 1990 to 2021.
  • Mortality rate showed a stable trend of -0.113% annually.
  • Increased contributions from non-alcoholic steatohepatitis in risk factors.
  • Projected increases in liver cancer cases but declining age-standardized rates by 2041.

Cite This Study

Wang et al. (2026) studied this question.

synapsesocial.com/papers/69c37b41b34aaaeb1a67d75bhttps://doi.org/10.1097/js9.0000000000005129
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Burden of liver cancer from 1990 to 2021 and modelled projection to 2040: insights from the global burden of disease study 20212026
  2. 2Global, regional and national burden of liver cancer in middle-aged and older adults from 1990 to 2021: a comprehensive analysis with cross-country inequality, decomposition, and frontier analysis2026
  3. 3Global, regional, and national burden of liver cancer due to hepatitis B, 1990–2021 and projections to 2051: a systematic analysis of the Global Burden of Disease Study 20212025 · 3 citations
  4. 4Global, Regional, and National Burden of Liver Cancer from 1990 to 2021 and Projections to 2050: A Global Burden of Disease Study 20212026
  5. 5[Epidemiological characteristics of liver cancer in China and worldwide].2025