What question did this study set out to answer?

To estimate the global, regional, and national burden of liver cancer among middle-aged and older adults from 1990 to 2021, addressing cross-country inequalities.

July 3, 2026Clinical and Translational GastroenterologyOpen Access

Global, regional and national burden of liver cancer in middle-aged and older adults from 1990 to 2021: a comprehensive analysis with cross-country inequality, decomposition, and frontier analysis

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Authors

WSWeifan SuiJiangsu University YDYuxin DuanJiangsu University ZCZefeng CaiJiangsu University

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Implication

Comprehensive analysis reveals increasing liver cancer burden in middle-aged and older adults, highlighting inequalities and dynamics.

Key Points

To estimate the global, regional, and national burden of liver cancer among middle-aged and older adults from 1990 to 2021, addressing cross-country inequalities.
Utilized age-standardized rates (ASRs) and estimated annual percentage changes (EAPCs) for analysis.
Applied decomposition analysis and frontier analysis to understand burden dynamics.
Assessed prevalence, incidence, deaths, and disability-adjusted life years (DALYs) rates over the period.
In 2021, liver cancer prevalence, incidence, deaths, and DALYs numbers increased compared to 1990.
Age-standardized death and DALYs rates slightly decreased, with higher burden observed in males versus females.
Population growth was the main driver of increased burden; aging and epidemiological changes contributed to reductions.

Cite This Study

Sui et al. (2026) studied this question.

synapsesocial.com/papers/6a47545e5c29257aa2579f64 https://doi.org/10.14309/ctg.0000000000001064

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Global, regional and national burden of liver cancer in middle-aged and older adults from 1990 to 2021: a comprehensive analysis with cross-country inequality, decomposition, and frontier analysis

Discussion

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Implication

Key Points

Cite This Study

Global, regional and national burden of liver cancer in middle-aged and older adults from 1990 to 2021: a comprehensive analysis with cross-country inequality, decomposition, and frontier analysis

Discussion

Member takes

Implication

Key Points

Cite This Study

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