The Paediatric Intensive Care Adaptive Platform Trial (PIVOTAL): Turning Pediatric Critical Care Practice Into Clinical Research

Key Points

• PIVOTAL aims to connect pediatric critical care with clinical research to create meaningful evidence for practice.
• Initiating recruitment for the trial in March 2026.
• Developing an adaptive platform to facilitate research and clinical care integration.
• Focusing on inclusivity and timely evidence delivery.
• Research outcomes are expected to lead to significant changes in pediatric critical care practices.
• Improved infrastructure is anticipated to enhance evidence collection and application.