Why the study?
Is serum indoxyl sulfate level associated with cardiac dysfunction and prognosis in patients with dilated cardiomyopathy?
Is serum indoxyl sulfate level associated with cardiac dysfunction and prognosis in patients with dilated cardiomyopathy?
Serum indoxyl sulfate levels may serve as a novel prognostic biomarker for patients with dilated cardiomyopathy and preserved or mildly impaired renal function.
Serum IS may mark prognosis in DCM with preserved renal function; leaves open prospective validation before clinical use.
Cardiac dysfunction is associated with the serum IS level, which might serve as a new prognostic marker in DCM patients with normal renal function or mild to moderate CKD.
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Shimazu et al. (2012) studied this question.
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