Key result
Clozapine-associated myocarditis presents with marked CRP elevation preceding cardiac biomarker rise and LV dysfunction.
Why the study?
Clozapine is associated with rare and potentially life-threatening myocarditis, but early clinical manifestations are often nonspecific and may delay diagnosis.
Case Report (n=1)
Monitoring inflammatory markers like C-reactive protein may help identify evolving clozapine-associated myocarditis before overt myocardial injury develops.
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Supports CRP monitoring during clozapine initiation to allow earlier intervention; extends limited evidence but remains hypothesis-generating.
Roomiany et al. (2026) conducted a case report in Clozapine-associated myocarditis (n=1). Clozapine was evaluated. Clozapine-associated myocarditis presented with a marked elevation in C-reactive protein (up to 174.1 mg/L) that preceded cardiac biomarker elevation and left ventricular systolic dysfunction.
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