Incidence and predictors of new persistent benzodiazepine and Z-drug use after critical illness A nationwide cohort study

Tak Kyu Oh; In‐Ok Song

doi:10.1097/eja.0000000000002395

March 24, 2026European Journal of Anaesthesiology

Incidence and predictors of new persistent benzodiazepine and Z-drug use after critical illness A nationwide cohort study

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Key Points

This research aims to identify the incidence and predictors of new persistent benzodiazepine and Z-drug use following critical illness.
Nationwide cohort study of ICU survivors
Analysis of pre-ICU medication exposure
Evaluation of psychiatric comorbidities
Approximately 16% of ICU survivors developed new persistent benzodiazepine use
Female sex and psychiatric comorbidities are significant risk factors
Pre-ICU exposure to SSRIs and opioids increases risk for persistent use

Implication

Cohort study reveals high incidence of persistent benzodiazepine use in ICU survivors, suggesting risk factors.

Abstract

Nearly one in six ICU survivors developed new persistent BZRA use. Along with psychiatric comorbidities and female sex, pre-ICU exposure to SSRIs and opioids identified patients at particularly high risk.

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Cite This Study

Oh et al. (2026) studied this question.

synapsesocial.com/papers/69c4ccaffdc3bde448918249 https://doi.org/10.1097/eja.0000000000002395

View Full Paper

Ask AI

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Incidence and predictors of new persistent benzodiazepine and Z-drug use after critical illness A nationwide cohort study

Key Points

Implication

Abstract

Discussion

Cite This Study

Incidence and predictors of new persistent benzodiazepine and Z-drug use after critical illness A nationwide cohort study

Key Points

Implication

Abstract

Discussion

Cite This Study

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