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March 26, 2026Critical Care Medicine

1361: Fluid Overload as a Predictor of Mortality and Organ Dysfunction in the Picu: A Retrospective Study

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Authors

FJFatima JamshaidSHSyed Muhammad Dayyan HassanASAbia ShahidKing Edward Medical University

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Overview

Retrospective study evaluates fluid overload effects on mortality and morbidity in critically ill children, indicating a need for careful monitoring.

Key Points

  • The study aims to evaluate the relationship between fluid overload in the first week of PICU admission and subsequent morbidity and mortality in pediatric patients.
  • Conducted a single-center, retrospective cohort study at Aga Khan University Hospital over four years.
  • Included patients aged 1 month to 18 years who stayed in PICU for more than 48 hours.
  • Collected data on fluid accumulation, mortality, length of stay, mechanical ventilation duration, and MODS occurrences.
  • Out of 2,874 PICU admissions, 1,633 were eligible and 84.5% had positive fluid overload.
  • Mortality rate was 10.7% in the fluid overload group compared to 6.3% in the non-fluid overload group.
  • Fluid accumulation over 10% at 24 and 48 hours correlated with higher mortality rates.

Cite This Study

Jamshaid et al. (2026) studied this question.

synapsesocial.com/papers/69c4cd65fdc3bde4489199fdhttps://doi.org/10.1097/01.ccm.0001187440.45039.15
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