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September 7, 2013Heart358 citations

Atrial fibrillation and thromboembolism in patients with hypertrophic cardiomyopathy: systematic review

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OGOliver GuttmannMRMohammad Shafiqur RahmanCOConstantinos O’Mahony

Structured PICO

P
Population
Patients with hypertrophic cardiomyopathy (HCM)
O
Outcome
Atrial fibrillation and thromboembolism

In patients with hypertrophic cardiomyopathy, atrial fibrillation is common and associated with high thromboembolic risk, warranting anticoagulation, with LA dimension and age being independent predictors.

Limitations

  • literature is insufficient to create robust clinical tools to predict AF or thromboembolism

Abstract

AF is common in HCM and associated with high thromboembolic risk. LA dimension and age are independently associated with AF but the literature is insufficient to create robust clinical tools to predict AF or thromboembolism. Most data suggest that AF patients should be anticoagulated.

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Cite This Study

Guttmann et al. (2013) studied this question.

synapsesocial.com/papers/69c5e6dc7090fce65e4ad853https://doi.org/10.1136/heartjnl-2013-304276
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Clinical Features and Outcome of Patients with Apical Hypertrophic Cardiomyopathy in Taiwan2006 · 27 citations
  2. 2Assessment of intravascular and extravascular mechanisms of myocardial perfusion abnormalities in obstructive hypertrophic cardiomyopathy by myocardial contrast echocardiography2007 · 53 citations
  3. 3Clinical Impact of Atrial Fibrillation in Patients With Hypertrophic Cardiomyopathy Results From Kochi RYOMA Study2009 · 100 citations
  4. 4A985G Polymorphism of the Endothelin-2 Gene and Atrial Fibrillation in Patients With Hypertrophic Cardiomyopathy2007 · 27 citations
  5. 5Left Ventricular Remodeling of Hypertrophic Cardiomyopathy Longitudinal Observation in a Rural Community2006 · 34 citations