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March 27, 2026AntibioticsOpen Access

Genetic Characterization of Carbapenem-Resistant Acinetobacter spp. Isolated from Diseased Companion Animals in Japan

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Authors

SHSaki HaradaMMMari MatsudaYHYuta Hosoi

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Overview

Surveillance study identifies carbapenem resistance mechanisms in diseased companion animals, suggesting monitoring needs.

Key Points

  • This study investigates the prevalence and genetic mechanisms of carbapenem resistance in Acinetobacter spp. from companion animals in Japan.
  • Isolates collected from diseased dogs and cats across Japan from 2020 to 2023
  • Antimicrobial susceptibility testing performed on 139 isolates
  • Whole-genome sequencing conducted on carbapenem-resistant isolates to identify resistance genes
  • Resistance rates to tested antimicrobials were below 20%
  • Meropenem resistance identified in three strains: A. radioresistens, A. proteolyticus, and A. johnsonii
  • First report of blaNDM-1-harboring Acinetobacter from companion animals in Japan

Cite This Study

Harada et al. (2026) studied this question.

synapsesocial.com/papers/69c61ff615a0a509bde18527https://doi.org/10.3390/antibiotics15040329
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Also Consider

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  4. 4Monitoring antimicrobial resistance trends and emerging carbapenemases in Enterobacterales causing companion animal infections: a four-year study2026
  5. 5Phenotypic Investigation and Detection of Biofilm-Associated Genes in Acinetobacter baumannii Isolates, Obtained from Companion Animals2024 · 9 citations