Key result
Use early echocardiography to evaluate peripartum cardiomyopathy in postpartum collapse even if pulmonary embolism is identified.
This case highlights the need to consider peripartum cardiomyopathy in postpartum collapse despite an identified pulmonary embolus, emphasizing the role of early echocardiography and biomarkers.
Urges caution against anchoring on PE in postpartum collapse; extends differential to peripartum cardiomyopathy and supports early echocardiography.
A woman in her 30s underwent elective caesarean delivery under spinal anaesthesia. Within minutes of delivery, she developed respiratory distress and shock with hypoxaemia. Chest radiography showed symmetrical, predominantly basal alveolar opacities. CT pulmonary angiography demonstrated a small subsegmental right lower lobe pulmonary embolus with bilateral ground-glass change. Point-of-care echocardiography revealed left ventricular systolic dysfunction (left ventricular ejection fraction ~35–40%) with regional hypokinesis and no right ventricular strain; natriuretic peptide and troponin were markedly elevated. Peripartum cardiomyopathy was diagnosed. She received oxygen, vasopressors and diuretics, and—once haemostasis was secure—staged escalation to therapeutic anticoagulation for the subsegmental embolus. Guideline-directed heart failure therapy was initiated and up-titrated. She improved and was discharged with a cardiology follow-up. This case highlights the need to consider peripartum cardiomyopathy in postpartum collapse despite an identified pulmonary embolus and emphasises early echocardiography, biomarkers and multidisciplinary management.
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Hussain et al. (2026) studied this question. Peripartum cardiomyopathy must be considered in postpartum collapse using early echocardiography to detect reduced ejection fraction (LVEF ~35-40%), even if a pulmonary embolus is identified.
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