What question did this study set out to answer?

To investigate the relationship between psychological stress and periodontal health, including underlying mechanisms and treatment outcomes.

The interplay between stress and periodontal health: A systematic review

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To investigate the relationship between psychological stress and periodontal health, including underlying mechanisms and treatment outcomes.
Conducted a systematic review of studies published from January 2000 to July 2025.
Searched databases including PubMed, Scopus, Web of Science, and Google Scholar.
Included human studies assessing stress with validated scales or biomarkers alongside periodontal parameters.
Assessed methodological quality with Newcastle–Ottawa Scale, Cochrane Risk of Bias Tool, and AMSTAR checklist.
Twenty-seven studies met the inclusion criteria, showing a positive association between higher stress and worse periodontal outcomes.
Elevated cortisol and immune dysregulation were noted as key mediators in the relationship.
Behavioral changes such as poor hygiene and smoking also contributed to worsening periodontal health.
Individuals under stress exhibited poorer responses to periodontal therapy.

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This systematic review explores how psychological stress affects periodontal health, suggesting implications for treatment.

Kumari et al. (2025) studied this question.

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