o-Amino aryl carbonyl compounds as Key Building Blocks for Green Synthesis of Quinoline Derivatives

o-Amino aryl carbonyl derivatives constitute an important class of intermediates in synthetic and medicinal chemistry owing to their tendency to undergo intramolecular condensation and cyclization under relatively mild conditions. The exceptional reactivity of these scaffolds makes them irreplaceable precursors for the production of a wide variety of nitrogen-containing heterocycles, such as quinolines, quinazolines, and benzodiazepines. Among this group of compounds, quinolines are particularly important due to their vast pharmacological potential and widespread use in pharmaceuticals, agrochemicals, and materials science. The review aims to provide an overview of recent developments in the synthesis, reactivity, and applications of quinolines derived from the cyclization of o-amino-substituted aryl carbonyl compounds, with a special focus on their involvement in green and sustainable chemistry strategies, such as solvent-free conditions and environmentally friendly catalytic systems.