Demonstrates a silver-catalyzed cycloaddition that produces chiral indolyl pyrroles, implying new pathways for drug development.
An atropoenantioselective Ag-catalysed [3+2] cycloaddition of N-alkynyl ketones with isocyanides has been developed to access 5−5-membered 1,3'-indolyl pyrroles bearing C-N axial chirality in high yields and excellent enantioselectivities. The resulting...
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Deng et al. (2026) studied this question.
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