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March 29, 2026Pediatric Blood & Cancer0 citations

When Neuromuscular Weakness Is Not Chemotherapy‑Related: Spinal Muscular Atrophy Type II Diagnosed After Acute Lymphoblastic Leukemia Onset in a 1‐Year‐Old Child: A Case Report and Review of the Literature

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FRFrancesca RomaniAzienda Ospedaliera San GerardoFCFrancesca CattaneoAzienda Ospedaliera San GerardoEVEmanuele VillaFondazione Lanza

Key Points

  • To highlight a rare diagnosis of spinal muscular atrophy type II in a child with acute lymphoblastic leukemia.
  • Reviewed the clinical history of a 1-year-old presenting with neuromuscular weakness.
  • Conducted diagnostic assessments to differentiate between causes of weakness.
  • Reviewed existing literature on similar cases and outcomes.
  • Confirmed diagnosis of spinal muscular atrophy type II after ruling out chemotherapy-related causes.
  • Discussion of differential diagnosis contributed to understanding misdiagnosis.
  • Emphasized the importance of thorough evaluation in pediatric cases involving neuromuscular symptoms.

Abstract

The authors declare no conflicts of interest.

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Cite This Study

Romani et al. (2026) studied this question.

synapsesocial.com/papers/69c8c247de0f0f753b39c853https://doi.org/10.1002/1545-5017.70278
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Also Consider

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  1. 1Spinal Muscular Atrophy: New Thoughts on the Pathogenesis and Classification Schema1992 · 84 citations
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  5. 5Myopathies in Early Infancy: An Overview and a Case of Early Onset Anti-NXP2-Positive Juvenile Dermatomyositis2025