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March 29, 2026MedicineOpen Access

Recurrent intracranial hemorrhage secondary to congenital factor XIII deficiency: A case report and literature review

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Authors

XZXu ZichaoXWXu WeiYHYu Hai

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Overview

Case report reveals recurrent intracranial hemorrhage in a male due to factor XIII deficiency, suggesting need for early diagnosis.

Key Points

  • This report examines recurrent intracranial hemorrhage due to congenital factor XIII deficiency and emphasizes diagnostic challenges.
  • Case report of a 53-year-old male with recurrent ICH.
  • Patient underwent two surgeries to evacuate intracerebral hematomas.
  • Ongoing treatment included cryoprecipitate therapy and postoperative CT scan monitoring.
  • Patient regained full consciousness after treatment.
  • CT scans showed significant resolution of the hematoma by discharge.
  • Monitoring and weekly cryoprecipitate infusions were planned post-discharge.

Cite This Study

Zichao et al. (2026) studied this question.

synapsesocial.com/papers/69c8c28cde0f0f753b39ce84https://doi.org/10.1097/md.0000000000047969
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Acquired factor XIII deficiency presenting with multiple intracranial hemorrhages and right hip hematoma: A case report2024 · 1 citations
  2. 2Unmasking Factor XIII Deficiency: Recurrent Intracranial Hemorrhage Despite Normal Coagulation Studies2026
  3. 3Factor XIII deficiency leading to a life-threatening intracranial hemorrhage in a young female: a case report2024 · 2 citations
  4. 4Multiple Cerebral Infarctions after Treatment of Acquired Factor XIII Deficiency with Retroperitoneal Hematoma2024 · 1 citations
  5. 5Intracranial Bleeding in a Neonate2024