Outpatient penicillin allergy de-labeling in primary care—whom to target

Angie Ton; Dan Ilges

doi:10.1017/ash.2026.10331

January 1, 2026Antimicrobial Stewardship & Healthcare EpidemiologyOpen Access

Outpatient penicillin allergy de-labeling in primary care—whom to target

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Key Points

Determine which patients with penicillin allergy labels should be targeted for de-labeling interventions.
Educated patients with penicillin allergy labels via online messaging.
Conducted allergy referrals through nurse-driven communication.
Analyzed the change in penicillin allergy labels before and after intervention.
Reduced penicillin allergy labels by 8.6%.
Largest reductions were seen in 'unknown' (14.8%) and 'rash' (7.9%) reaction types.
Smaller reductions were noted for 'hives' (6.1%) and 'itching' (1.4%).

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Implication

Education and nursing interventions reduce penicillin allergy labels in primary care, suggesting effective targeting strategies.

Abstract

Education and allergy referral via nurse-driven online messaging to patients (n = 1,284) with penicillin allergy labels (PALs) reduced PALs by 8.6%. The percentage decrease of “unknown” (14.8%) and “rash” (7.9%) PALs were higher vs “hives” (6.1%) and “itching” (1.4%) reaction types.

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Cite This Study

Ton et al. (2026) studied this question.

synapsesocial.com/papers/69c8c2a4de0f0f753b39d0b9 https://doi.org/10.1017/ash.2026.10331

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Outpatient penicillin allergy de-labeling in primary care—whom to target

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

Outpatient penicillin allergy de-labeling in primary care—whom to target

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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