What question did this study set out to answer?

To explore the link between early-life famine exposure and the risk of microvascular complications in adulthood for individuals with type 2 diabetes.

March 30, 2026Open Access

Longitudinal association between early-life famine exposure and risk of microvascular complications of type 2 diabetes in adulthood: A retrospective cohort in Tianjin, China.

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Authors

XCXiaocui ChengTianjin Infectious Diseases Hospital QWQi WuCentral South University WZWei ZhaoTianjin Infectious Diseases Hospital

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Implication

Retrospective cohort shows increased risk of microvascular complications in type 2 diabetes with early-life famine exposure, indicating implications for obesity and hypertension management.

Key Points

To explore the link between early-life famine exposure and the risk of microvascular complications in adulthood for individuals with type 2 diabetes.
Conducted a retrospective cohort study in Tianjin, China
Analyzed data on early-life famine exposure and prevalence of microvascular complications in adults with T2D
Evaluated associations with variables like hypertension and obesity
Exposure to famine in early life is associated with increased risks of microvascular complications, including DMC, DR, and DKD in adults with T2D.
The risk of diabetic retinopathy (DR) is particularly higher in those with hypertension.
Diabetic kidney disease (DKD) shows a stronger association with early-life famine exposure among individuals with hypertension or both general and abdominal obesity.

Cite This Study

Cheng et al. (2026) studied this question.

synapsesocial.com/papers/69c9c51bf8fdd13afe0bd069 https://doi.org/10.6133/apjcn.202604_35(2).0006

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Implication

Retrospective cohort shows increased risk of microvascular complications in type 2 diabetes with early-life famine exposure, indicating implications for obesity and hypertension management.

Longitudinal association between early-life famine exposure and risk of microvascular complications of type 2 diabetes in adulthood: A retrospective cohort in Tianjin, China.

Discussion

Member takes

Implication

Key Points

Cite This Study

Longitudinal association between early-life famine exposure and risk of microvascular complications of type 2 diabetes in adulthood: A retrospective cohort in Tianjin, China.

Discussion

Member takes

Implication

Key Points

Cite This Study

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