Why the study?
Complications after Watchman device implantation are rare, and delayed left circumflex artery occlusion associated with the device had not been previously reported.
Case Report (n=1)
No
This case report documents the first known instance of delayed-phase (2.5 years post-implantation) left circumflex artery occlusion caused by progressive expansion and extrinsic compression from a Watchman FLX device, highlighting the need for cautious device sizing and long-term monitoring when the LAA-to-LCx distance is <2 mm.
Potential delayed LCx occlusion after Watchman FLX expansion warrants awareness in sizing; leaves open optimal surveillance needs.
BACKGROUND: The Watchman device (Boston Scientific) is designed for left atrial appendage closure and has shown sufficient safety for clinical use. CASE SUMMARY: -VASc score: 4, HAS-BLED score: 3) and bronchiectasis with occasional hemoptysis who underwent successful percutaneous left atrial appendage closure with a 35-mm Watchman FLX device. The initial postoperative course was uneventful; however, she presented with persistent chest pain 2.5 years later. Computed tomography and coronary angiography revealed near-complete occlusion of the left circumflex artery. DISCUSSION: Complications after Watchman implantation are rare, and left circumflex artery occlusion associated with the device is extremely unusual, with no previous reports of such delayed coronary obstruction. TAKE-HOME MESSAGE: This case illustrates a unique chronic complication of Watchman implantation and the importance of careful anatomical evaluation and long-term follow-up.
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Kajiyama et al. (2026) conducted a case report in Chronic atrial fibrillation and delayed left circumflex artery occlusion after left atrial appendage closure (n=1). Percutaneous left atrial appendage closure with a 35-mm Watchman FLX device followed by emergency percutaneous coronary intervention with a 3.0 x 28 mm everolimus-eluting stent was evaluated on Delayed complete occlusion of the proximal left circumflex artery at 2.5 years post-Watchman FLX implantation and subsequent restoration of TIMI grade 3 flow via PCI.
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