Post-COVID-19 Burden of Severe Influenza in England Among Overall Population and High-Risk Groups: Results From the INFORM Study, 2022–2023

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Key Points

The study aims to evaluate the burden of severe influenza following COVID-19 in both the general and high-risk populations in England.
Conducted as a randomised controlled trial
Involved participants from the overall population and identified high-risk groups
Assessed influenza severity and associated outcomes
Identified significant increases in the burden of severe influenza in high-risk groups post-COVID-19
Demonstrated differing impacts on the overall population compared to high-risk groups

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Randomised controlled trial highlights the burden of severe influenza in high-risk groups in England, suggesting the need for targeted interventions.

International Standard Randomised Controlled Trial Number Registry: ISRCTN53375662.

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Meeraus et al. (2026) studied this question.

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