What question did this study set out to answer?

To evaluate the association between Chlamydia trachomatis infection and the risk of developing preeclampsia during pregnancy.

March 30, 2026Open Access

Chlamydia Trachomatis and the Development of Preeclampsia in Pregnancy

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Authors

TSTabraiz SA EAErskine A RNRamkissoon N

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Implication

Retrospective cohort study finds Chlamydia infection correlates with increased preeclampsia risk in pregnant individuals, suggesting the need for STI screening.

Key Points

To evaluate the association between Chlamydia trachomatis infection and the risk of developing preeclampsia during pregnancy.
Retrospective cohort study using TriNetX Research Network data
Identified pregnant individuals based on ICD-10 codes for Chlamydia infection
Utilized propensity score matching to control for confounding variables
Analyzed outcomes with various statistical methods including risk ratio and Kaplan Meier survival curves
Women with Chlamydia had a slightly higher incidence of preeclampsia (3.6% vs 3.5%)
Risk difference noted at 0.001 (P=0.042)
Risk ratio reported as 1.037 and odds ratio as 1.038
Significantly higher mean number of preeclampsia events in the Chlamydia group (4.43 vs 2.81; P<0.001)
No significant difference in time to onset of preeclampsia (P=0.164)

Cite This Study

SA et al. (2026) studied this question.

synapsesocial.com/papers/69ca1369883daed6ee0954f3 https://doi.org/10.5281/zenodo.19239087

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Implication

Retrospective cohort study finds Chlamydia infection correlates with increased preeclampsia risk in pregnant individuals, suggesting the need for STI screening.

Chlamydia Trachomatis and the Development of Preeclampsia in Pregnancy

Discussion

Member takes

Implication

Key Points

Cite This Study

Chlamydia Trachomatis and the Development of Preeclampsia in Pregnancy

Discussion

Member takes

Implication

Key Points

Cite This Study

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