Key result
Therapeutic propafenone for AFib can induce Type 1 Brugada ECG patterns, creating a diagnostic challenge.
Why the study?
Does therapeutic dose propafenone cause a Type 1 Brugada-Electrocardiogram in patients with atrial fibrillation?
Does therapeutic dose propafenone cause a Type 1 Brugada-Electrocardiogram in patients with atrial fibrillation?
Therapeutic doses of propafenone for atrial fibrillation may induce a Type 1 Brugada-Electrocardiogram pattern.
Answers are grounded in this paper and cite their sources.
Requires distinguishing propafenone-induced Brugada phenocopy from true syndrome in AF; extends evidence on therapeutic-dose effects.
Authors: Ioannis Vogiatzis , Evangelos Sdogkos , Aggelos Georgakopoulos Not available Keywords: Atrial fibrillation, propafenone, Brugada syndrome, Brugada phenocopy.
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Vogiatzis et al. (2026) studied this question. Therapeutic doses of propafenone for atrial fibrillation can induce a Type 1 Brugada-ECG pattern, creating a diagnostic challenge between true Brugada syndrome and a phenocopy.
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