Key result
Severe hypokalemia induced a clinically reproducible type 1 Brugada electrocardiogram pattern that resolved with potassium correction and recurred during a subsequent episode of hypokalemia.
Case Report (n=1)
This case report demonstrates the clinical reproducibility of Brugada phenocopy by showing the recurrence and resolution of a type 1 Brugada ECG pattern corresponding to recurrent hypokalemia.
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Supports reversible Brugada phenocopy with potassium correction; hypothesis-generating and should not yet change practice.
Brugada phenocopies (BrP) are clinical entities that are etiologically distinct from true congenital Brugada syndrome (BrS). BrP are characterized by type 1 or type 2 Brugada electrocardiogram (ECG) patterns in precordial leads V1 -V3 ; however, BrP are elicited by various underlying clinical conditions such as electrolyte disturbances, myocardial ischemia, or poor ECG filters. In this report, we describe the first case of clinically reproducible BrP which is important to the conceptual evolution of BrP.
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Genaro et al. (2013) conducted a case report in Brugada phenocopy (n=1). Hypokalemia vs. Normokalemia was evaluated on Electrocardiogram pattern changes. Severe hypokalemia induced a clinically reproducible type 1 Brugada electrocardiogram pattern that resolved with potassium correction and recurred during a subsequent episode of hypokalemia.
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