Key result
A Brugada Type-1 ECG pattern induced by severe electrolyte disturbances (hyperkalemia and hyponatremia) completely resolved upon normalization of electrolyte levels.
Case Report (n=1)
Clinicians must exclude reversible electrolyte causes before diagnosing Brugada syndrome; this case leaves open the prevalence and criteria for phenocopies.
Brugada syndrome (BrS) is an important cause of sudden cardiac death (SCD) with well-defined ST-segment elevation patterns on V1 -V3 . Observation of BrS-Type-electrocardiogram (ECG) patterns in medical conditions without true BrS is called "Brugada Phenocopy" (BrP). We present a case of 61-year-old male patient with hyperkalemia, hyponatremia, and BrS-Type-1 ECG pattern in the setting of acute postrenal failure. He was denying any syncope or family history of SCD. With normalization of electrolyte levels, BrS-Type-1-ECG resolved. Electrolyte disturbances are one of the most common reasons of BrP. Being aware of BrPs and differentiating from an unmasked BrS-ECG pattern could prevent patients from lethal consequences and unnecessary treatments.
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Hunuk et al. (2016) conducted a case report in Brugada Phenocopy induced by electrolyte disorder (n=1). Electrolyte disorder (hyperkalemia and hyponatremia) was evaluated on Resolution of Brugada Type-1 ECG pattern. A Brugada Type-1 ECG pattern induced by severe electrolyte disturbances (hyperkalemia and hyponatremia) completely resolved upon normalization of electrolyte levels.
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