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March 31, 2026Scientific Reports0 citationsOpen Access

Laser fluence dependent antibacterial activity of cadmium sulfide quantum dots prepared by one step laser ablation in liquid

KHKarrar M. HassanUniversity of Technology - IraqATAli A. TahaUniversity of Technology - IraqRIRaid A. IsmailUniversity of Technology - Iraq

Key Points

  • This research aims to explore how laser fluence affects the antibacterial properties of cadmium sulfide quantum dots.
  • Synthesized cadmium sulfide quantum dots using pulsed laser ablation in liquid at varying laser fluences.
  • Analyzed physical and chemical properties using techniques like XRD, FESEM, and TEM.
  • Evaluated antibacterial activity against Gram-negative and Gram-positive bacteria.
  • Determined minimum inhibitory concentrations for different bacterial strains.
  • CdS quantum dots exhibited a hexagonal wurzite structure with crystallite sizes between 6-11 nm.
  • Highest antibacterial activity observed in quantum dots synthesized at 7.64 J/cm² laser fluence.
  • Inhibition zones varied with quantum dot size and laser fluence, indicating size-dependent effects.

Abstract

Cadmium sulfide (CdS) quantum dots (QDs) were synthesized using pulsed laser ablation in liquid (PLAL) at different laser fluences. The effect of laser fluence on the optical, structural, morphological, and electrical properties of CdS QDs was investigated by using X-ray diffraction (XRD), field emission scanning electron microscopy (FESEM), energy-dispersive X-ray (EDX), zeta potential, photoluminescence (PL), transmission electron microscopy (TEM), UV–Visible absorption spectroscopy, and Fourier-transform infrared spectroscopy (FTIR). XRD analysis show that the synthesized CdS QDs have a hexagonal wurzite structure and the crystallite size was in the range of 6–11 nm. They also exhibit negative surface charge about − 2.7, − 18.2, and − 19.0 mV, all that for CdS QDs, which were prepared at 1.27, 3.82, and 7.64 J/cm², laser fluences, respectively. The antibacterial activity of the CdS QDs was evaluated against both Gram-negative bacteria (Escherichia coli, Pseudomonas aeruginosa) and Gram-positive bacteria (Staphylococcus aureus, Streptococcus agalactiae). The results showed varying inhibition zones depending on the concentration, surface deformation, and particle size of the CdS QDs, in which the smallest size QDs, which were prepared by using 7.64 J/cm² laser fluence, show higher inhibition zones than other particles. In addition, the minimum inhibitory concentration (MIC) was determined for each bacterial strain.

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Cite This Study

Hassan et al. (2026) studied this question.

synapsesocial.com/papers/69cb650ee6a8c024954b9210https://doi.org/10.1038/s41598-026-40885-w
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