Mathematical Comparison Between Radiotherapy and Chemotherapy in Tumor Control

Radiotherapy and chemotherapy act through distinct mechanisms, but both can be representedmathematically as terms that oppose tumor growth. In this work, a comparative modelling framework isproposed in which the same baseline tumor dynamics is combined separately with a radiotherapy termand a chemotherapy term. The resulting equations are analysed in order to compare effective growthreduction, cumulative treatment burden, and treatment-dependent equilibria. The study provides asimple mathematical basis for comparing the qualitative impact of local irradiation and systemic drugaction on tumor control.