July 1, 2004Pacing and Clinical Electrophysiology
Accuracy of Atrial Tachyarrhythmia Detection in Implantable Devices with Arrhythmia Therapies
Why the study?
Do AT500 and GEM III AT implantable devices accurately detect atrial tachyarrhythmias in patients with stored episodes?
Population
Patients with implantable devices (AT500 and GEM III AT) from four clinical trials
Comparison
AT500 and GEM III AT implantable devices with… vs Manual analysis of stored episodes and 24-hour…
Design
Meta-analysis
Authors
Discussion
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Implication
Supports reliable device-based atrial monitoring in practice; reinforces dual-chamber detection validity via meta-analysis.
Key Points
- The aim is to quantify inappropriate detection rates of atrial tachyarrhythmias in implantable devices.
- Meta-analysis of clinical trials assessing atrial tachyarrhythmia detection from two implantable devices.
- Manual analysis of 21,553 episodes from 1,142 patients.
- Comparison of detection rates between septal and nonseptal lead locations.
- Inappropriate detection primarily resulted from far-field R wave oversensing or premature atrial contractions.
- Adjusted detection rates were 95.3% for AT500 and 95.7% for GEM III AT.
- 100% detection of sustained atrial arrhythmia and 95.3% of net arrhythmia duration on Holter recordings.
Structured PICO
Do AT500 and GEM III AT implantable devices accurately detect atrial tachyarrhythmias in patients with stored episodes?
P
Population
Patients with implantable devices (AT500 and GEM III AT) from four clinical trials
I
Intervention
AT500 and GEM III AT implantable devices with dual chamber logic
C
Comparator
Manual analysis of stored episodes and 24-hour Holter recordings
O
Outcome
Percentage of appropriate atrial tachyarrhythmia detectionsurrogate
Implantable devices with dual-chamber logic demonstrate high accuracy (>95%) in detecting atrial tachyarrhythmias, validating their diagnostic reliability.
Cite This Study
Pürerfellner et al. (2004) studied this question.