Key result
Orthostatic hypotension in Parkinson disease is linked to ~10-fold greater fall risk and cognitive impairment.
Orthostatic hypotension affects an estimated 36% of people with Parkinson disease and requires standardized screening and a stepwise management approach.
Requires standardized screening and stepwise management in Parkinson disease; confirms its association with falls and cognitive impairment.
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Zhu et al. (2026) conducted a review in Parkinson disease with orthostatic hypotension. Stepwise management (nonpharmacologic and pharmacologic therapies) was evaluated. Orthostatic hypotension occurs in an estimated 36% of patients with Parkinson disease, increasing fall risk 10-fold and nearly tripling the risk of cognitive impairment.
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