What question did this study set out to answer?

The main goal was to describe the epidemiological profile of childhood-onset systemic lupus erythematosus and to compare the diagnostic criteria performance.

April 1, 2026Rheumatology and Immunology ResearchOpen Access

Comparative diagnostic performance of ACR 1997, SLICC 2012, and EULAR/ACR 2019 criteria in childhood-onset systemic lupus erythematosus: A retrospective study from a tertiary care centre in south India

View Full Paper

Ask AI

Bookmark

The main goal was to describe the epidemiological profile of childhood-onset systemic lupus erythematosus and to compare the diagnostic criteria performance.
Conducted a retrospective medical record review of children with diagnosed systemic lupus erythematosus
Excluded children with overlap connective tissue diseases
Applied ACR, SLICC, and EULAR/ACR classification criteria against physician diagnosis
Analyzed clinical and laboratory features to calculate sensitivity of each criteria
Included 66 children with confirmed cSLE
SLICC 2012 criteria showed 95.5% sensitivity, followed by EULAR/ACR 2019 at 93.9% and ACR 1997 at 84.8%
Common symptoms included fever (83%), alopecia (70%), and others
4.5% cases missed all criteria

Discussion

No takes yet. Share an insight, caveat, or question.

Implication

This retrospective study evaluates classification criteria for childhood lupus, revealing important diagnostic performance differences.

Cite This Study

Mahadevan et al. (2026) studied this question.

synapsesocial.com/papers/69ccb6fd16edfba7beb88c4a https://doi.org/10.1515/rir-2026-0006

View Full Paper

Ask AI

Bookmark

Comparative diagnostic performance of ACR 1997, SLICC 2012, and EULAR/ACR 2019 criteria in childhood-onset systemic lupus erythematosus: A retrospective study from a tertiary care centre in south India

Key Points

Discussion

Implication

Cite This Study

Comparative diagnostic performance of ACR 1997, SLICC 2012, and EULAR/ACR 2019 criteria in childhood-onset systemic lupus erythematosus: A retrospective study from a tertiary care centre in south India

Key Points

Discussion

Implication

Cite This Study

Keep reading

Keep reading