Key result
Larger CT-measured systolic tricuspid annulus area is linked to ~77% higher odds of moderate-to-severe FTR.
Why the study?
The study was conducted to examine the relationship between each severity of functional tricuspid regurgitation and morphological evaluation on contrast-enhanced CT.
Do morphological changes of the tricuspid valve complex measured on contrast-enhanced CT correlate with functional tricuspid regurgitation severity grade?
Observational (n=45)
Do morphological changes of the tricuspid valve complex measured on contrast-enhanced CT correlate with functional tricuspid regurgitation severity grade?
Morphological parameters such as tricuspid annulus area and right ventricular volume measured on contrast-enhanced CT correlate positively with functional tricuspid regurgitation severity, with systolic tricuspid annulus area being a strong predictor of moderate or severe disease.
CT systolic TA area may help identify moderate or severe FTR; extends morphological evaluation but remains hypothesis-generating.
PURPOSE: To examine the relationship between each severity of functional tricuspid regurgitation (FTR) and morphological evaluation on contrast-enhanced computed tomography (CT). METHODS: Forty-five patients underwent contrast-enhanced CT. Tricuspid annulus area (TAA), tricuspid annulus circumference (TAC), right ventricular volume (RVV), and the distances between the tips and bases of the papillary muscles were measured on contrast-enhanced CT in diastole and systole. The patients were classified organized into 4 groups by TR grade measured by transthoracic echocardiography (none+trivial: 26, mild: 6, moderate: 6, severe: 7), and the data were compared among the groups. RESULTS: In parameters measured on contrast-enhanced CT images, TAA, TAC, and the distances between the tips of the anterior and posterior papillary muscles in both diastole and systole and RVV in diastole were significantly different among the groups (p<0.05). Parameters that had correlations with TR grade were TAA, TAC, RVV and the distances between the tips of the anterior and posterior papillary muscles in both diastole and systole (r>0.40). The septal papillary muscle could not be identified in about 1/3 (35.6%) of cases. CONCLUSIONS: TAA, TAC, RVV, and the distance between the tips of the anterior and posterior papillary muscles measured on contrast-enhanced CT images had relatively positive correlations with TR grade.
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Hiroki et al. (2022) conducted an observational in Functional tricuspid regurgitation (n=45). Contrast-enhanced computed tomography vs. Transthoracic echocardiography (TR grade) was evaluated on Risk factors for moderate or severe functional tricuspid regurgitation (OR 1.77, 95% CI 1.26-2.49, p=0.001). Systolic tricuspid annulus area measured on contrast-enhanced CT was significantly associated with moderate or severe functional tricuspid regurgitation (OR 1.77).
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