Key result
Severe functional tricuspid regurgitation was associated with significantly larger tricuspid valve annulus dimensions and commissural distances compared to controls.
Why the study?
The study was conducted to assess TV geometrical changes in functional TR using novel CT scan parameters focusing on commissures and correlate them with echocardiography.
What are the geometrical changes of the tricuspid valve assessed by cardiac CT in patients with severe functional tricuspid regurgitation compared to controls?
Observational (n=86)
No
What are the geometrical changes of the tricuspid valve assessed by cardiac CT in patients with severe functional tricuspid regurgitation compared to controls?
Novel CT variables focusing on commissures demonstrate significant geometrical changes, including a more circular annulus and larger dimensions, in patients with severe functional tricuspid regurgitation.
Answers are grounded in this paper and cite their sources.
CT annulus/commissural metrics may refine severe functional TR assessment; leaves open prospective validation before guiding therapy.
BACKGROUND: Cardiac computed tomography (CT) provides important insights into the geometrical configuration of the tricuspid valve (TV). The purpose of the present study was to assess the geometrical changes of TV in patients with functional tricuspid regurgitation (TR) using novel CT scan parameters and to correlate these findings with echocardiography. METHODS: This single-center study enrolled 86 patients undergoing cardiac CT and divided them into two groups according to the presence or not of severe TR (43 patients with TR ≥ 3+ and 43 controls). The measurements collected were as follows: TV annulus area and perimeter, septal-lateral and antero-posterior annulus diameters, eccentricity, distance between commissures, segment between the geometrical centroid and commissures, and the angles of commissures. RESULTS: We found a significant correlation between all annulus measurements and the grade of TR, except in regard to angles. TR ≥ 3+ patients had significantly larger TV annulus area and perimeter, larger septal-lateral, and antero-posterior annulus dimensions, as well as larger commissural distance and centroid-commissural distance. In patients with TR ≥ 3+ and controls, the eccentricity index predicted a circular shape and an oval shape of the annulus, respectively. CONCLUSIONS: These novel CT variables focusing on commissures increase the anatomical understanding of the TV apparatus and the TV geometrical changes in patients with severe functional TR.
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Cammalleri et al. (2023) conducted an observational in Functional tricuspid regurgitation (n=86). Severe functional tricuspid regurgitation (TR ≥ 3+) vs. Controls was evaluated on Tricuspid valve geometrical changes (annulus area, perimeter, dimensions, eccentricity, and commissural distances). Severe functional tricuspid regurgitation was associated with significantly larger tricuspid valve annulus dimensions and commissural distances compared to controls.
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