Key result
Novel computed tomography parameters of the tricuspid valve annulus demonstrated significant phasic variability during the cardiac cycle and predicted the annulus area.
Why the study?
CT is recommended to define anatomical suitability for transcatheter technologies and plan tricuspid valve interventions, motivating the assessment of tricuspid valve geometrical characteristics using novel CT parameters.
Observational (n=22)
No
Novel CT-derived annular parameters of the tricuspid valve demonstrate phasic variability and predict annulus area, potentially aiding in transcatheter intervention planning.
May aid tricuspid intervention planning; hypothesis-generating and requires prospective validation before adoption.
BACKGROUND: Computed tomography (CT) is the recommended imaging technique for defining the anatomical suitability for current transcatheter technologies and planning tricuspid valve (TV) intervention. The aim of the Tricuspid Regurgitation IMAging (TRIMA) study was to assess the geometrical characteristics of the TV complex using novel CT parameters. METHODS: This prospective, single-center study enrolled 22 consecutive patients with severe tricuspid regurgitation, who underwent a cardiac CT study dedicated to the right chambers. The following variables were obtained: annulus area and perimeter, septal-lateral and antero-posterior diameters, tenting height, and anatomical regurgitant orifice area. Moreover, the following novel annular parameters were assessed: distance between commissures, distance between TV centroid and commissures, and angles between centroid and commissures. RESULTS: A significant phasic variability during the cardiac cycle existed for all variables except for eccentricity, angles, and distance between the postero-septal and antero-posterior commissure and distance between the centroid and antero-posterior commissure. There was a significant relationship between the TV annulus area and novel annular parameters, except for annular angles. Additionally, novel annular variables were found to predict the annulus area. CONCLUSIONS: These novel additional variables may provide an initial platform from which the complexity of the TV annular morphology can continue to be better understood for further improving transcatheter therapies.
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Cammalleri et al. (2022) conducted an observational in Severe tricuspid regurgitation (n=22). Cardiac CT study dedicated to the right chambers was evaluated on Geometrical characteristics of the tricuspid valve complex using novel CT parameters. Novel computed tomography parameters of the tricuspid valve annulus demonstrated significant phasic variability during the cardiac cycle and predicted the annulus area.
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