Key result
Higher waist circumference is linked to increased postprandial triglycerides, independent of fasting levels.
Why the study?
Does waist circumference correlate better with postprandial triglyceride levels compared to fasting triglyceride levels in adults not on diabetes or dyslipidemia medications?
Cross-Sectional (n=2,303)
Does waist circumference correlate better with postprandial triglyceride levels compared to fasting triglyceride levels in adults not on diabetes or dyslipidemia medications?
Effect estimate: standardized β=0.10 in men and standardized β=0.15 in women
p-value: p=<0.001
Postprandial triglyceride levels correlate more strongly with waist circumference than fasting triglyceride levels, suggesting postprandial measurements may better reflect central adiposity-related metabolic risk.
Aim: Postprandial hypertriglyceridemia is recognized as an independent risk factor for cardiovascular disease. The aim of this study was to identify differences between fasting and postprandial TG levels, focusing on the influence of waist circumference. Methods: Subjects included 1,505 men and 798 women aged 3865 years who were not taking medications for diabetes or dyslipidemia. Fasting TG levels were measured after an overnight fast, and postprandial TG levels were measured 2 hours after a standardized rice-based lunch (total 740 kcal, 20 g fat, 30 g protein, and 110 g carbohydrates) in the afternoon on the same day. Results: Fasting and postprandial TG levels were highly correlated in both men (r=0.86, p<0.001) and women (r=0.84, p<0.001). Waist circumference was positively correlated with fasting TG (r=0.38 in men and r=0.36 in women) and postprandial TG (r=0.42 in men and r=0.45 in women), respectively. On multiple regression analyses, the association of waist circumference with postprandial TG was still significant (standardized β=0.10 in men and standardized β=0.15 in women, p<0.001) after the inclusion of HbA1c, age, high-density-lipoprotein (HDL)-cholesterol, alcohol consumption, and fasting TG in the regression model. Conclusion: Postprandial TG has a better relation with waist circumference than fasting TG.
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Oka et al. (2009) reported a cross-sectional. Waist circumference was evaluated on Association of waist circumference with postprandial triglyceride levels (standardized β=0.10 in men and standardized β=0.15 in women, p=<0.001). Waist circumference was significantly associated with postprandial triglyceride levels in both men (standardized β=0.10) and women (standardized β=0.15) (p<0.001), independent of fasting levels.
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