Why the study?
How do different platelet function tests compare in evaluating aspirin response and repeatability in healthy individuals and patients with coronary artery disease?
Population
Patients with stable coronary artery disease (n=43) and healthy individuals (n=21)
Comparison
Aspirin treatment evaluated by multiple platelet… vs Comparison between different platelet function…
Design
Cohort
Follow-up
4 days
Authors
Loading...
Discordant test results warrant caution in aspirin monitoring; leaves open assay standardization for research and practice.
How do different platelet function tests compare in evaluating aspirin response and repeatability in healthy individuals and patients with coronary artery disease?
Conclusions regarding aspirin responsiveness depend heavily on the specific platelet function assay used, with VerifyNow demonstrating the highest reproducibility and correlation with serum thromboxane.
Hvas et al. (2010) studied this question.