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Introduce Simpleaffy, a software package integrated into BioConductor designed to facilitate standardized quality assessment and downstream data analysis for Affymetrix microarrays.

August 2, 2005Bioinformatics

Simpleaffy: a BioConductor package for Affymetrix Quality Control and data analysis

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Authors

CWClaire WilsonUniversity of Glasgow CMCrispin MillerCancer Research UK

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Implication

Software note presents Simpleaffy for automated quality control in Affymetrix microarray experiments, highlighting streamlined high-throughput genomic data processing.

Key Points

Introduce Simpleaffy, a software package integrated into BioConductor designed to facilitate standardized quality assessment and downstream data analysis for Affymetrix microarrays.
Developed within the R and BioConductor open-source statistical environments to handle Affymetrix probe-level data.
Engineered automated algorithms to calculate standardized quality control metrics, generate diagnostic plots, and manage differential gene expression workflows.
Provides an integrated pipeline enabling researchers to flag problematic Affymetrix hybridizations before final biological analysis.
Distributes package functions, tutorials, and supporting documentation through an institutional web repository.

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Wilson et al. (2005) studied this question.

synapsesocial.com/papers/69cecbdb978f5f183732aef1 https://doi.org/10.1093/bioinformatics/bti605

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Implication

Software note presents Simpleaffy for automated quality control in Affymetrix microarray experiments, highlighting streamlined high-throughput genomic data processing.

Simpleaffy: a BioConductor package for Affymetrix Quality Control and data analysis

Discussion

Member takes

Implication

Key Points

Cite This Study

Simpleaffy: a BioConductor package for Affymetrix Quality Control and data analysis

Discussion

Member takes

Implication

Key Points

Cite This Study

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