The actual state of impaired glucose tolerance in young Japanese people and its relationship with physique

Purpose: Inappropriate diet among young people has been linked to a greater prevalence of ill health and lifestyle diseases in younger generations.Despite this, health examinations of young people targeting early detection of lifestyle diseases are not being carried out.In particular, there are hardly any reports of the oral glucose tolerance test (OGTT) being performed on young people.We therefore examined the actual state of impaired glucose tolerance (IGT) and its association with body mass index (BMI) and body fat percentage in past data on 75 g OGTT results from university students.Methods: A total of 1,772 healthy university students (200 men and 1,572 women, mean age of 20.4 0.6 years, BMI of 20.5 2.4 kg/m 2 ) were given a 75 g OGTT and had their body composition measured. 2 tests and Fisher's exact tests were performed to examine the association between OGTT blood glucose level and BMI as well as body fat percentage.Logistic regression analysis was performed on the factors affecting having a blood glucose level of 180 mg/dl or higher measured one hour after the glucose load (one-hour blood glucose level).Results: IGT was present in 34.0% of men and 45.1% of women, and the proportion of those with a one-hour blood glucose level of 180 mg/dl or higher was 21.0% for men and 37.8% for women.Both proportions were significantly higher for women.However, no association with BMI or body fat percentage was observed.Logistic regression analysis adjusted for sex, fasting blood glucose level, BMI, and body fat percentage was performed to determine the factors affecting a one-hour blood glucose level of 180 mg/dl or higher and the results revealed an odds ratio of 2.89 (95% confidence interval, 1.84-4.54)for women compared to men.Conclusion: IGT was observed in about 40% of young people who were not obese, and the risk of IGT was higher for women.However, no association with BMI or body fat percentage was observed.Further studies are needed to determine the factors affecting IGT in young women.