The QDOT Micro catheter achieved 100% acute pulmonary vein isolation and similar 12-month freedom from atrial arrhythmia recurrence between the QMode+ solely (90%) and hybrid (88%) modalities.
Observational (n=982)
Yes
Does very high-power short-duration radiofrequency ablation using the QDOT Micro catheter effectively and safely achieve pulmonary vein isolation in patients with paroxysmal or persistent atrial fibrillation?
Very high-power short-duration radiofrequency ablation using the QDOT Micro catheter is safe and effective for achieving pulmonary vein isolation in patients with atrial fibrillation, yielding high 12-month freedom from recurrence.
Absolute Event Rate: 90% vs 88%
p-value: p=ns
The QDOT Micro catheter allows to perform a very high-power short-duration ablation that produces wider and shallower lesions. This study aims to corroborate the evidences on the safety, acute and long-term efficacy of this catheter by providing a large real-world dataset. The AIR HPSD Registry is a multicentric prospective registry across 26 European centers that enrolled consecutive atrial fibrillation (AF) patients undergoing their first pulmonary vein (PV) isolation. In all patients a wide antrum circumferential ablation aimed at PV isolation was performed using the QDOT Micro catheter in QMode+ (90 w for 4 s) for the whole ablation or in a hybrid mode (QMode + for the posterior wall and QMode guided by ablation index for the anterior wall), according to the operators’ preference. Overall, 982 patients have been enrolled, 38% of patients were ablated with the QMode + solely and 62% with a hybrid modality. The fluoroscopy time was higher in the hybrid group (396 ± 493 s vs. 138 ± 238 s, p < 0.001) and similarly the procedural time (112 ± 41 min vs. 96 ± 36 min, p = 0.01). The complications (1.8%) were similar between groups (1.1% in Qmode+ group vs. 2.3% in hybrid group, p = 0.3). The freedom from AF/AT recurrence was similar between groups (88% hybrid group vs. 90% Qmode+ group, p = ns) and higher in paroxysmal than in persistent patients (90% vs. 81%, p < 0.001). The QDOT Micro catheter demonstrated high efficiency, safety, and effectiveness in achieving PV isolation in patients undergoing their first ablation for paroxysmal or persistent AF.
Strisciuglio et al. (Tue,) conducted a observational in Atrial fibrillation (n=982). QDOT Micro catheter (QMode+ solely) vs. Hybrid modality (QMode+ and ablation index-guided) was evaluated on Freedom from atrial fibrillation or atrial tachycardia recurrence (p=ns). The QDOT Micro catheter achieved 100% acute pulmonary vein isolation and similar 12-month freedom from atrial arrhythmia recurrence between the QMode+ solely (90%) and hybrid (88%) modalities.