Researchers investigate dyslipidemia's impact on blood and saliva in rats, suggesting BDNF's role in lipid metabolism.
Saliva testing provides considerable information and is noninvasive.Although dyslipidemia alters blood components, its effects on saliva remain unclear.We investigated these changes using a dyslipidemia rat model.Three-week-old male rats were fed with high-fat or control diet for 10 weeks.Blood, saliva, salivary gland, and liver were collected for histological and biochemical analyses.We showed that dyslipidemia causes fatty liver and increases levels of triglycerides and brain-derived neurotrophic factor (BDNF) in blood and saliva, suggesting BDNF regulates lipid metabolism.
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To et al. (2018) studied this question.
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