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Spinal Cord Stimulation, Peripheral Nerve Stimulation, and Pulsed Radiofrequency in the Management of Herpes Zoster–Related Pain: A Network Meta-Analysis

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Network meta-analysis reveals superior pain relief from combination therapies in herpes zoster pain, indicating effective management options.

To compare the effectiveness of spinal cord stimulation, peripheral nerve stimulation, and pulsed radiofrequency in managing herpes zoster-related pain.
Conducted a network meta-analysis
Evaluated multiple neuromodulation therapies
Assessed improvements in pain relief and sleep quality
SCS combined with PRF showed superior pain relief compared to other therapies
PNS combined with PRF and PNS alone improved sleep quality significantly
SCS was effective in reducing the need for pregabalin and improving SF-36 scores

Sabet et al. (2026) studied this question.

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Network meta-analysis reveals superior pain relief from combination therapies in herpes zoster pain, indicating effective management options.