3P Clinical significance of achieving no evidence of disease in HER2-positive metastatic breast cancer: A multicenter study by Turkish Oncology Group (TOG)

B. Dursun; S. Yaslikaya; Serhat Sekmek; Tuğba Önder; H.C. Yildirim; O. Acar; N. Sever; Savaş Gökçek; S. Ön; F. Aslan; G.S.Y. Keskin; Z. Sucuoglu Isleyen; Gözde Savaş; M.E. Kalender; Öznur Bal; Ü Y Arslan; M. Sahbazlar; B. Cakar; H.M. Türk; H. Akbulut

doi:10.1016/j.esmoop.2026.106106

Key Points

This research aims to explore the clinical significance of achieving no evidence of disease in HER2-positive metastatic breast cancer and identify predictive factors.
Conducted a multicenter study across various oncology centers
Analyzed clinical data of patients with HER2-positive metastatic breast cancer
Evaluated the association between achieving no evidence of disease and treatment outcomes
Found that achieving no evidence of disease is linked to improved disease control
Identified key predictive factors influencing the likelihood of achieving no evidence of disease
Highlights the potential role of no evidence of disease as a meaningful treatment goal

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Implication

Multicenter study shows predictive factors for achieving no evidence of disease in HER2-positive metastatic breast cancer, indicating its importance in treatment outcomes.

Abstract

Achieving no evidence of disease (NED) in HER2-positive metastatic breast cancer (MBC) has been proposed as a surrogate for durable disease control. However, its clinical significance and predictive factors are not yet well established.

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Cite This Study

Dursun et al. (2026) studied this question.

synapsesocial.com/papers/69cf5d4e5a333a821460aff7 https://doi.org/10.1016/j.esmoop.2026.106106

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3P Clinical significance of achieving no evidence of disease in HER2-positive metastatic breast cancer: A multicenter study by Turkish Oncology Group (TOG)

Key Points

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Implication

Abstract

Discussion

Cite This Study

3P Clinical significance of achieving no evidence of disease in HER2-positive metastatic breast cancer: A multicenter study by Turkish Oncology Group (TOG)

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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