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Analysis demonstrates how intrathoracic pressure changes affect PCWP interpretation in ventilation, indicating potential clinical implications.
Because the pulmonary capillary is located in the thorax, measurements of pulmonary capillary wedge pressure (PCWP) are influenced by changes in intrathoracic pressure produced by positive-pressure ventilation. Interpretation of PCWP should be made at end-expiration, when airway pressures and atmospheric pressures equilibrate.
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Gooding et al. (1977) studied this question.
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