Demonstrates the synthesis of quinolinyl-enone esters in high yield, indicating potential for advanced chemical applications.
A copper-catalyzed, 100% atom-economic coupling of quinoline N-oxides with electron-deficient alkynes yields quinolinyl-enone esters (up to 99%, 100:1 high regioselectivity). This protocol facilitates late-stage functionalization and construction of novel BF2...
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Wang et al. (2025) studied this question.
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