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Findings suggest that miR-335-5p can serve as a biomarker for wet age-related macular degeneration, indicating its diagnostic potential.
MiR-335-5p may have a high diagnostic value in wAMD, suggesting that miR-335-5p might be a biomarker of wAMD. VEGFA was the target of miR-335-5p, and the two were negative correlation in wAMD. MiR-335-5p regulates VEGFA secretion in RPE cells, thereby indirectly participating in the core pathological process of wAMD.
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Chen et al. (2026) studied this question.
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