A Miniaturized Enzymatic Lactate Sensor for Continuous Monitoring in Oxygen-Depleted Tissue Microenvironments

C. Chen; Vishal Venkatesh; Eiko Nakamaru-Ogiso; Zarazuela Zolkipli-Cunningham; Marni J. Falk; Vernon Anderson; Mark G. Allen

doi:10.1109/tbme.2026.3679466

January 1, 2026IEEE Transactions on Biomedical Engineering

A Miniaturized Enzymatic Lactate Sensor for Continuous Monitoring in Oxygen-Depleted Tissue Microenvironments

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Key Points

The aim is to develop a miniaturized enzymatic sensor for continuous lactate monitoring in low-oxygen environments.
Developed a miniaturized enzymatic sensor for lactate detection
Tested sensor performance in controlled oxygen-depleted conditions
Evaluated the sensor's capability for continuous monitoring over time
The sensor successfully measures lactate levels in real-time
Demonstrated sensitivity to changes in lactate concentrations
Showed potential for practical use in monitoring ischemia and cancer

Implication

This sensor enables real-time metabolic assessment in oxygen-depleted tissues, suggesting applications in health monitoring.

Abstract

The sensor provides a platform for real-time metabolic assessment to support diagnostics, longitudinal health monitoring, and evaluation of therapeutic response in conditions such as ischemia and cancer.

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Cite This Study

Chen et al. (2026) studied this question.

synapsesocial.com/papers/69cf5eee5a333a821460db84 https://doi.org/10.1109/tbme.2026.3679466

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A Miniaturized Enzymatic Lactate Sensor for Continuous Monitoring in Oxygen-Depleted Tissue Microenvironments

Key Points

Implication

Abstract

Discussion

Cite This Study

A Miniaturized Enzymatic Lactate Sensor for Continuous Monitoring in Oxygen-Depleted Tissue Microenvironments

Key Points

Implication

Abstract

Discussion

Cite This Study

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