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Thrombotic Microangiopathy And Hypertensive Emergency After Cocaine Use: A Case Report

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To discuss the case of thrombotic microangiopathy and hypertensive emergency after cocaine use, exploring underlying mechanisms.
Evaluated patient presentation and laboratory findings including blood tests and kidney biopsy.
Assessed hemolysis pattern and ADAMTS13 activity to rule out TTP.
Administered blood pressure management and initiated eculizumab treatment.
Patient exhibited hypertensive emergency and microangiopathic hemolytic anemia after cocaine use.
Kidney biopsy confirmed acute thrombotic microangiopathy.
Blood pressure management improved hemodynamics; however, kidney function initially worsened before stabilizing.

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A case report reveals thrombotic microangiopathy following cocaine use in a patient, suggesting complex mechanisms.

Moreno-Mirón et al. (2026) studied this question.

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