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This case highlights the association between cocaine use and ANCA vasculitis, especially in severe presentations.

C48-35 Cocaine-Associated ANCA Vasculitis Presenting as Pulmonary-Renal Syndrome Requiring ECMO Salvage Therapy

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This case highlights the association between cocaine use and ANCA vasculitis, especially in severe presentations.
Detailed clinical and serological evaluation of a patient with recent cocaine abuse.
Utilization of immunosuppressive therapy and ECMO to manage severe pulmonary-renal pathology.
Monitoring and assessment of clinical status throughout hospitalization.
Patient presented with severe anemia (Hgb 7.0 g/dL) and acute kidney injury (Cr 1.7 mg/dL).
Positive ANCA serology confirmed the diagnosis of ANCA-associated vasculitis.
Successfully weaned off ECMO after 2 weeks, indicating effective management despite initial decline.

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Case report shows ANCA vasculitis manifests as pulmonary-renal syndrome in a woman, emphasizing prompt treatment.

Haines et al. (2026) studied this question.

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